Thomas Cook is removing all its customers from a hotel in Egypt after the death of a British couple.
John Cooper, 69, and his wife Susan, 63, from Burnley, Lancashire, died at the Steigenberger Aqua Magic in the Red Sea resort of Hurghada.
Mr Cooper is understood to have suffered a heart attack on Tuesday. The cause of his wife's death is unclear.
Thomas Cook said had it received "further reports of a raised level of illness among guests".
In a statement, Thomas Cook said 301 holidaymakers will have options for alternative hotels from Friday onwards and those wishing to go home will be flown back on Friday.
It added: "Safety is always our first priority, so as a precautionary measure we have taken a decision to remove all our customers from this hotel.
"While we understand this is upsetting for those on holiday, we believe this is the right thing to do."
'Tired and exhausted'
Other guests have told the BBC about their experiences with illness during stays at the Steigenberger Aqua Magic.
Janine Traviss, from Oldham, and her partner fell ill with a stomach bug during a holiday which ended earlier this month.
"I subsequently have been ill for several weeks now since returning and had to visit the doctors on two occasions with two full weeks of antibiotics.
"I am still recovering and still feel very tired and exhausted most days."
Thomas Cook said it is working closely with the hotel and is supporting the local authorities with their investigations.
It stated that the hotel was last audited late last month and received an overall score of 96%.
"We will be contacting those customers due to travel to the Steigenberger Aqua Magic Hotel in Hurghada in the next four weeks to offer alternative holiday options," the tour operator added.
Mrs Cooper worked at the travel firm's Burnley branch, which was closed on Thursday.
She was earlier described as "loyal and long-serving" member of staff by the company.
The listing for the hotel on the Thomas Cook website includes a line saying: "Sorry, there is currently no availability."
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